Mitomycin C | 50-07-7

Mitomycin C is a chemotherapy medication used primarily in the treatment of various types of cancer. It belongs to a class of drugs known as antineoplastic antibiotics. Mitomycin C works by interfering with the growth and replication of cancer cells, ultimately causing their death.

Here are some key points about Mitomycin C:

Mechanism of Action: Mitomycin C works by binding to DNA and inhibiting its replication. It cross-links DNA strands, preventing them from separating during cell division, which ultimately leads to cell death.

Indications: Mitomycin C is commonly used to treat certain types of cancer, including stomach (gastric) cancer, pancreatic cancer, anal cancer, bladder cancer, and certain types of lung cancer. It may also be used in combination with other chemotherapy drugs or radiation therapy.

Administration: Mitomycin C is typically administered intravenously by a healthcare professional in a clinical setting such as a hospital or infusion center.

Side Effects: Common side effects of Mitomycin C may include nausea, vomiting, diarrhea, fatigue, and decreased blood cell counts (anemia, leukopenia, thrombocytopenia). It may also cause more serious side effects such as bone marrow suppression, kidney toxicity, and pulmonary toxicity.

Precautions: Due to its potential for toxicity, Mitomycin C should be used with caution, especially in patients with pre-existing kidney or liver problems. Patients receiving Mitomycin C should be closely monitored for signs of adverse effects.

Usage in Cancer Treatment: Mitomycin C is often used as part of combination chemotherapy regimens or in conjunction with other cancer treatments to improve outcomes in patients with various types of cancer.